Polyclonal Antibody to Caspase-12

Product code: 11-1016

Clonality : Polyclonal
Application : WB
Reactivity : Human

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Available Pack Size(s)

  •   25 µg

  •  100 µg

  • $100.00 

  • $270.00 

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Shipping Info:

Order now and get it on Tuesday November 19, 2024

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Format : Purified
Amount : 100 µg
Isotype : Rabbit IgG
Purification : Protein A Chromatography
Content : 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : CASP12
Gene ID : 100506742
Uniprot ID : Q6UXS9
Alternative Name : CASP12, UNQ9415/PRO34398
Immunogen Information : A partial length recombinant Caspase-12 protein (amino acids 100-321) was used as the immunogen for this antibody.

Caspase 12 belongs to a family of enzymes called caspases that is highly related to members of the ICE subfamily. Other caspases cleave their substrates at C-terminal aspartic acid residue but caspase 12 does not have protease properties rather it processes inflammatory cytokines. It is involved in the activation cascade of caspases responsible for apoptosis execution. Diseases associated with CASP12 include sepsis and prion disease. Caspase 12 is mainly expressed in skeletal muscle and lung.

Western blot analysis: 4-6 µg/ml

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Tissue Specificity: Detected in heart, kidney, liver, lung, pancreas, small intestine, spleen, stomach, thymus and testis.
BioGrid: 125680. 10 interactions.
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