Polyclonal Antibody to Cadherin-17
Fig-1: Expression analysis of Cadherin-17. Anti-Cadherin-17 antibody (11-7542) was used at 1 µg/ml on h Intestine lysate.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Rabbit IgG |
| Purification : | Protein A Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles. |
Cadherin-17 (CDH17), acts as a unique member of cadherin family mediating cell-cell adhesion, expresses exclusively in human intestinal and pancreatic ductal epithelial cells,which is not supposed to be found in healthy stomach. This protein is also called LI (Liver Intestine) cadherin or HPT-1 (Human Peptide Transporter-1) and is a structurally unique member of the cadherin superfamily. Whereas the so-called classic cadherins, such as E-, N- and P-cadherin, have five cadherin repeats within the extracellular domain, CDH17 consists of seven cadherin repeats.
Western blot analysis: 1-2 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cell membrane |
| Tissue Specificity: | Expressed in the gastrointestinal tract and pancreatic duct. Not detected in kidney, lung, liver, brain, adrenal gland and skin. |
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