Polyclonal Antibody to beta-Catenin (Ab-654) (Discontinued)

Product code: 35-1733

Clonality : Polyclonal
Application : WB
Reactivity : Rat, Mouse, Human

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Format : Purified
Amount : 100 µg
Isotype : Rabbit IgG
Content : Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : CTNNB1
Gene ID : 1499
Uniprot ID : P35222
Alternative Name : CTNNB1, CATNB, CTNB1, CTNNB
Immunogen Information : Peptide sequence around aa.652~656 (A-T-Y-A-A) derived from Human b-Catenin.

Involved in the regulation of cell adhesion and in signal transduction through the Wnt pathway.

Predicted MW: 92kd, Western blotting: 1:500~1:1000

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cytoplasm, Nucleus, Cytoplasm, Cell junction, Cell junction, Cell membrane, Cytoplasm, Cytoplasm, Cell junction, Cytoplasm
Post transnational modification: Deacetylated at Lys-49 by SIRT1.
Tissue Specificity: Expressed in several hair follicle cell types: basal and peripheral matrix cells, and cells of the outer and inner root sheaths. Expressed in colon. Present in cortical neurons (at protein level). Expressed in breast cancer tissues (at protein level) (PubMed:29367600).
BioGrid: 107880. 630 interactions.
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