Anti-IL18 Polyclonal Antibody
Figure 1: Anti-IL-18 antibody(39-2159). Lanes: Anti-IL-18(39-2159) at 0.5ug/ml. Lane 1: Rat Spleen Tissue Lysate at 40ug, Lane 2: Rat Thymus Tissue Lysate at 40ug, Lane 3: PC12 Whole Cell Lysate at 40ug. Predicted band size: 22 kDa. Observed band size: 22 kDa.
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| Amount : | 100 μg/vial |
| Isotype : | Rabbit IgG |
| Purification : | Immunogen affinity purified. |
| Content : | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. Reconstitute : Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
| Storage condition : | At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing. |
| Gene : | Il18 |
| Gene ID : | 29197 |
| Uniprot ID : | P97636 |
| Alternative Name : | Interleukin-18; IL-18; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; IL-1 gamma; Il18; Igif |
| Immunogen Information : | E.coli-derived rat IL18 recombinant protein (Position: H37-S194). Rat IL18 shares 64% and 91% amino acid (aa) sequence identity with human and mouse IL18, respectively. |
Interleukin (IL)-18, also called Interferon-gamma-inducing factor (IGIF), augments natural killer (NK) activity in spleen cells. The gene encodes a precursor protein of 192 amino acids and a mature protein of 157 amino acids. IL18 is a recently discovered cytokine that modulates both T helper type 1 (Th1) and Th2 responses. IL18 is a potent proinflammatory cytokine with potential atherogenic properties. It is highly expressed in the atherosclerotic plaques compared with control normal arteries and is localized mainly in plaque macrophages.
Western blot : 0.1-0.5μg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Secreted |
| Post transnational modification: | The pro-IL-18 precursor is processed by CASP1 or CASP4 to yield the active form. |
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