Anti-Fos B Polyclonal Antibody
Figure 1: Anti-Fos B antibody(39-2009). Western blotting: Lanes: Anti Fos B(39-2009) at 0.5ug/ml, Lane 1: Rat Kidney Tissue Lysate at 50ug, Lane 2: HEPG2 Whole Cell Lysate at 40ug. Predicted band size: 36 kDa. Observed band size: 36 kDa.
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| Format : | Lyophilized |
| Amount : | 100 μg/vial |
| Isotype : | Rabbit IgG |
| Purification : | Immunogen affinity purified. |
| Content : | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. Reconstitute : Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
| Storage condition : | At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing. |
| Gene : | FOSB |
| Gene ID : | 2354 |
| Uniprot ID : | P53539 |
| Alternative Name : | Protein fosB; G0/G1 switch regulatory protein 3; FOSB; G0S3 |
| Immunogen Information : | A synthetic peptide corresponding to a sequence at the C-terminus of Human Fos B (264-291aa LPFQTSQDAPPNLTASLFTHSEVQVLGD), different from the related Mouse sequence by two amino acids. |
FOSB, FBJ murine osteosarcoma viral oncogene homolog B, is a protein that, in humans, is encoded by the FOSB gene. FOSB is a member of Fos gene family which consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. The FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. The FOSB gene is mapped to 19q13.32. Delta FOSB is a truncated splice variant of FOSB. Delta FosB has been implicated in the development of drug addiction and control of the reward system in the brain, and is linked to changes in a number of other gene products such as CREB and sirtuins. Delta FosB also regulates the commitment of mesenchymal precursor cells to the adipocyte or osteoblast lineage.
Western blot : 0.1-0.5μg/ml; Immunohistochemistry(Paraffin-embedded Section) : 0.5-1μg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Nucleus |
| BioGrid: | 108637. 8 interactions. |
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