Polyclonal Antibody to Anti-ATF6 Antibody(Discontinued)
Figure 1: Anti-ATF6 antibody(39-2023). Western blotting: Lanes: Anti ATF6 39-2023 at 0.5ug/ml. WB: A549 Whole Cell Lysate at 40ug. Predicted band size: 75 kDa. Observed band size: 90 kDa.
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| Amount : | 100 μg/vial |
| Isotype : | Rabbit IgG |
| Purification : | Immunogen affinity purified. |
| Content : | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitute : Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
| Storage condition : | At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing. |
| Gene : | ATF6 |
| Gene ID : | 22926 |
| Uniprot ID : | P18850 |
| Alternative Name : | Cyclic AMP-dependent transcription factor ATF-6 alpha; cAMP-dependent transcription factor ATF-6 alpha; Activating transcription factor 6 alpha; ATF6-alpha |
| Immunogen Information : | A synthetic peptide corresponding to a sequence in the middle region of human ATF6(390-405aa LNYGPMSMLEQDSRRM), different from the related mouse and rat sequences by two amino acids. |
ATF6, a member of the leucine zipper protein family, is an endoplasmic reticulum(ER) stress-regulated transmembrane transcription factor that activates the transcription of ER molecules. ATF6 gene is mapped to chromosome 1q23.3. ATF6 can constitutively induce the promoter of glucose-regulated protein(grp) genes through activation of the endoplasmic reticulum(ER) stress element(ERSE).
Western blot : 0.1-0.5μg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Nucleus |
| Post transnational modification: | Phosphorylated in vitro by MAPK14/P38MAPK. |
| Tissue Specificity: | Ubiquitous. |
| BioGrid: | 116586. 48 interactions. |
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