Polyclonal Antibody to Alpha-synuclein
Figure-1: Immunofluorescent analysis of a section of rat cerebellum stained with chicken pAb to α-synuclein,(34-1112), dilution 1:3,000 in red, and costained with rabbit pAb to GFAP,(34-1042), dilution 1:5,000 in green. The blue is DAPI staining of nuclear DNA. Following transcardial perfusion of rat with 4% paraformaldehyde, brain was post fixed for 24 hours, cut to 45μM, and free-floating sections were stained with above antibodies. The α-synuclein protein is concentrated in presynaptic regions in the granular and molecular layers, while GFAP antibody stains the network of Bergmann and astroglial cells.
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| Format : | Purified |
| Amount : | 100 µl |
| Isotype : | Chicken, IgY |
| Content : | Antibody is supplied as an aliquot of 1 mg/ml affinity purified antibody |
| Storage condition : | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles. |
WB: 1:2,000 IF/ICC and IHC: 1:1,000
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cytoplasm, Membrane, Nucleus, Cell junction, Secreted |
| Post transnational modification: | Acetylation at Met-1 seems to be important for proper folding and native oligomeric structure. |
| Tissue Specificity: | Highly expressed in presynaptic terminals in the central nervous system. Expressed principally in brain. |
| BioGrid: | 112506. 474 interactions. |
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