Polyclonal Antibody to Adenylate Cyclase III(Discontinued)

Product code: 34-1003

Clonality : Polyclonal
Application : IHC, WB
Reactivity : Pig, Rat, Mouse, Human, Bovine

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Format : Purified
Amount : 100 µl
Isotype : Rabbit, IgG
Content : Supplied as an aliquot of affinity purified at 1 mg/ml.
Storage condition : Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : Adcy3
Gene ID : 64508
Uniprot ID : P21932
Alternative Name : ATP pyrophosphate-lyase 3, AC-III, Adenylate cyclase type III, Adenylate cyclase, olfactive type, AC3, Adenylyl cyclase 3
Immunogen Information : C-terminal peptide of rat ACIII, PAAFPNGSSVTLPHQVVDNP with a Cys added to the N-terminus to allow coupling to KLH.

Western blots: 1:5,000-1:10,000. ICC/IF or IHC: 1:500-1:1,000.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

1. Bowie E, Goetz SC. TTBK2 and primary cilia are essential for the connectivity and survival of cerebellar Purkinje neurons. Elife. 2020 Jan 14;9. pii: e51166. doi: 10.7554/eLife.51166. [Epub ahead of print] PubMed PMID: 31934864.

Subcellular location: Cell membrane, Golgi apparatus, Cell projection, Cytoplasm
Post transnational modification: Rapidly phosphorylated after stimulation by odorants or forskolin. Phosphorylation by CaMK2 at Ser-1076 down-regulates enzyme activity.
Tissue Specificity: Detected on cilia on the olfactory epithelium (at protein level) (PubMed:2255909, PubMed:25908845). Detected on cilia on the olfactory epithelium.
BioGrid: 249093. 1 interactions.
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