Phospho-Stat6 (Tyr641) (Clone: G12) rabbit mAb APC conjugate

Product code: 12-4143

Clone name : Stat6Y641-G12
Clonality : Monoclonal
Application : FACS
Reactivity : Human, Mouse
Conjugate : APC

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  •   10 Tests

  •  100 Tests

  • $392.00 

  • $629.00 

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For estimated delivery dates, please contact us at [email protected]


Format : Conjugated
Amount : 100 Tests
Isotype : Rabbit IgG1k
Content : 1X PBS, 0.09% NaN3, 0.2% BSA
Storage condition : Store at 2-8°C. Avoid repeated freeze and thaw cycles.
Alternative Name : Signal transducer and activator of transcription 6, IL-4 Stat
Immunogen Information : A synthetic phospho-peptide corresponding to residues surrounding Tyr641 of human phospho Stat6
The transcription factor Stat6 is a member of the signal transducers and activators of transcription (STAT) family of proteins. Stat6 is the only member of this family that is activated by interleukin-4 (IL-4), after which Stat6 is both tyrosine- and serine-phosphorylated by Jak kinases. The consensus Stat6 binding site TTCN4GAA is found in the promoters of many genes regulated by IL-4. In T lymphocytes, Stat6 is required for differentiation into Th2 cells in response to IL-4. Stat6 may play a role in solid tumorigenesis; a large immunohistochemistry study of Stat6 expression in over 2,000 tumor samples confirmed strong nuclear staining.

For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells or 5 µL per 100 µL of staining volume. It is recommended that the reagent be titrated for optimal performance for each application.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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