PerCP-Cy5.5 Conjugated Anti-CD34 / Mucosialin Monoclonal Antibody (Clone:QBEnd-10)

Product code: 30-1028PC-Cy5.5

Clone name : QBEnd-10
Clonality : Monoclonal
Application : FACS
Reactivity : Human, Non-Human Primates

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100 tests
$550.00 

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Amount : 100 tests
Isotype : Mouse IgG1
Purification : Purified antibody is conjugated with activated tandem dye of activated Peridinin-Chlorophyll Protein-Cyanine 5.5 (PerCP-Cy5.5) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Content : Formulation: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide Storage and handling
Storage condition : Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Gene : CD34
Gene ID : 947
Uniprot ID : P28906
Immunogen Information : Human endothelial vesicles
CD34 is a highly glycosylated monomeric 111-115 kDa surface protein, which is present on many stem cell populations. It is a well established stem cell marker, though its expression on human hematopoietic stem cells is reversible. CD34 probably serves as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions.
Specificity:The antibody QBEnd-10 reacts with an extracellular class II epitope on CD34, a 110-115 kDa monomeric transmembrane phosphoglycoprotein expressed on hematopoietic progenitors cells and on the most pluripotential stem cells; it is gradually lost on progenitor cells. This antibody has been also used as an endothelial marker.

Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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