PE-Cy5 Conjugated Anti-CD34 / Mucosialin Monoclonal Antibody (Clone:4H11[APG])
Figure 1: Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD34 (4H11[APG]) PE-Cy5 antibody (4 μl reagent / 100 μl of peripheral whole blood).
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Amount : | 100 tests |
Isotype : | Mouse IgG1 |
Purification : | Purified antibody is conjugated with activated tandem dye of R-phycoerythrin-cyanine 5 (PE-Cy5) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography. |
Content : | Formulation: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
Storage condition : | Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze. |
CD34 is a highly glycosylated monomeric 111-115 kDa surface protein, which is present on many stem cell populations. It is a well established stem cell marker, though its expression on human hematopoietic stem cells is reversible. CD34 probably serves as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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