PE-conjugated Anti-IL13 antibody(1A1), IgG1 Chimeric mAb
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| Amount : | 100 test |
| Isotype : | Rabbit/Human Fc chimeric IgG1 |
| Purification : | Purified from cell culture supernatant by affinity chromatography |
| Content : | Liquid?PBS?with?0.05%?Proclin300,?1%?BSA |
| Storage condition : | Store?at?2?C-8?C?for?6?months |
| Gene : | IL13 |
| Uniprot ID : | P35225 |
| Alternative Name : | IL-13;NC30 |
This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]
FACS 1:100
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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