PE Conjugated Anti-Human CD151 (Clone : 50-6)
Figure 1: Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD151 (50-6) PE antibody
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Amount : | 100 tests |
Isotype : | Mouse IgG1 kappa |
Purification : | The purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography. |
Content : | Formulation : Stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide |
Storage condition : | Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. |
Gene : | CD151 |
Gene ID : | 977 |
Alternative Name : | RAPH blood group, MER2, SFA1, PETA-3, GP27,CD151 molecule (Raph blood group) |
Immunogen Information : | Human epidermoid carcinoma cell line Hep-3 |
CD151, also known as PETA-3 (platelet-endothelial tetraspan antigen), is a four-pass transmembrane glycoprotein with short cytoplasmic N- and C-termini. CD151 is expressed mainly in platelets and megakaryocytes, immature hematopoietic cells, activated T cells, in endothelium, muscle cells, and epithelial cells. It associates with CD9, CD181, and integrin complexes alpha 3 / beta 1 (CD49c / CD29), alpha 5 / beta 1 (CD49e / CD29), and alpha 6 / beta 4 (CD49f / CD104). CD151 appears to be involved in cell adhesion and migration, including metastasis.
Specificity : The mouse monoclonal antibody CD151 recognizes an extracellular epitope of CD151 (also known as PETA-3), a 29 kDa transmembrane protein of tetraspanin family, expressed in many cell types.
Flow cytometry: The reagent is designed for analysis of human blood cells using 10 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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