PE Conjugated Anti-DLL4 (Clone : MHD4-46)

Product code: 30-2532PE

Clone name : MHD4-46
Clonality : Monoclonal
Application : FACS
Reactivity : Human
Conjugate : PE

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0.1 mg
$468.00 

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Amount : 0.1 mg
Isotype : Mouse IgG1 kappa
Purification : The purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Content : 0.1 mg/ml
Formulation : Stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Gene : DLL4
Gene ID : 54567
Alternative Name : Delta like ligand 4, AOS6, canonical Notch ligand 4,delta like canonical Notch ligand 4
Immunogen Information : recombinant soluble human DLL4

DLL4 (Delta-like 4) is one of five ligands of Notch receptors. It interacts with Notch1 and Notch4. DLL4 is up-regulated at sites of physiologic and pathologic angiogenesis, whereas its expression is low in most adult normal tissues. It is also highly expressed in human clear-cell renal carcinomas, bladder cancers, and breast cancers. Blocking the DLL4-Notch interaction seems to be a promissing therapeutic approach.
Specificity : The mouse monoclonal antibody MHD4-46 recognizes the extracellular domain of DLL4 (Delta-like ligand 4), a type I transmembrane protein which plays an important role in vascular development.

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