PE Conjugated Anti-CD300e / IREM-2 Monoclonal Antibody (Clone:UP-H2)

Product code: 30-2359PE

Clone name : UP-H2
Clonality : Monoclonal
Application : FACS
Reactivity : Human
Conjugate : PE

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Price
100 tests
$468.00 

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For estimated delivery dates, please contact us at [email protected]


Amount : 100 tests
Isotype : Mouse IgG1
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Gene : CD300E
Gene ID : 342510
Uniprot ID : Q496F6
Alternative Name : CD300E, CD300LE, CLM2, CMRF35A5, IREM2
Immunogen Information : CD300e-HA-transfected cells

CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers.

Subcellular location: Cell membrane
Post transnational modification: N-glycosylated.
Tissue Specificity: Present on the surface of mature hematopoietic cells of the monocyte and myeloid lineages (at protein level).
BioGrid: 131180. 8 interactions.
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