NFNB Recombinant Protein

Product code: 32-2605

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20 µg
$388.00 

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Amount : 20 µg
Purification : Greater than 95.0% as determined by SDS-PAGE.
Content : 1mg/ml solution containing 20mM Tris pH-8, 1mM DTT, 0.05M NaCl & 10% glycerol.
Storage condition : NFNB Human although stable at 4C for 1 week, should be stored desiccated below -18C. Please prevent freeze thaw cycles.
AA sequence : MGSSHHHHHH SSGLVPRGSH MDIISVALKR HSTKAFDASK KLTPEQAEQI KTLLQYSPSS TNSQPWHFIV ASTEEGKARV AKSAAGNYVF NERKMLDASH VVVFCAKTAM DDVWLKLVVD QEDADGRFAT PEAKAANDKG RKFFADMHRK DLHDDAEWMA KQVYLNVGNF LLGVAALGLD AVPIEGFDAA ILDAEFGLKE KGYTSLVVVP VGHHSVEDFN ATLPKSRLPQ NITLTEV.
Alternative Name : DPRA, NFSB, NFSI, NTR.
Source : Escherichia Coli. NFNB Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 237 amino acids (1-217 a.a.) and having a molecular mass of 26 kDa. The NFNB is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. NFNB demonstrates the capability to reduce quinines. NFNB enzyme activates prodrugs in antibody directed enzyme prodrug therapy. NFNB reduces nitrofurazone, quinones and anti-tumor agent CB1954 (5-(aziridin-1-yl)-2,4-dinitrobenzamide). The reduction of CB1954 results in the generation of cytotoxic species.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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