NFNB Recombinant Protein
Shipping Info:
For estimated delivery dates, please contact us at [email protected]
Amount : | 20 µg |
Purification : | Greater than 95.0% as determined by SDS-PAGE. |
Content : | 1mg/ml solution containing 20mM Tris pH-8, 1mM DTT, 0.05M NaCl & 10% glycerol. |
Storage condition : | NFNB Human although stable at 4C for 1 week, should be stored desiccated below -18C. Please prevent freeze thaw cycles. |
AA sequence : | MGSSHHHHHH SSGLVPRGSH MDIISVALKR HSTKAFDASK KLTPEQAEQI KTLLQYSPSS TNSQPWHFIV ASTEEGKARV AKSAAGNYVF NERKMLDASH VVVFCAKTAM DDVWLKLVVD QEDADGRFAT PEAKAANDKG RKFFADMHRK DLHDDAEWMA KQVYLNVGNF LLGVAALGLD AVPIEGFDAA ILDAEFGLKE KGYTSLVVVP VGHHSVEDFN ATLPKSRLPQ NITLTEV. |
Alternative Name : | DPRA, NFSB, NFSI, NTR. |
Source : Escherichia Coli.
NFNB Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 237 amino acids (1-217 a.a.) and having a molecular mass of 26 kDa. The NFNB is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
NFNB demonstrates the capability to reduce quinines. NFNB enzyme activates prodrugs in antibody directed enzyme prodrug therapy. NFNB reduces nitrofurazone, quinones and anti-tumor agent CB1954 (5-(aziridin-1-yl)-2,4-dinitrobenzamide). The reduction of CB1954 results in the generation of cytotoxic species.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
There are currently no product reviews
|