NFAT Reporter Assay

ABEOMICS custom NFAT reporter assay utilizes the proprietary NFAT reporter cell line system. Nuclear factor of activated T cells (NFAT) is a transcription factor that is found in activated T lymphocytes as well as other immune cells including dendritic cells, B cells and megakaryocytes. NFAT reporter system is designed to monitor the transcriptional activity of NFAT. NFAT reporter assay services include screening of agonists/antagonists that affect the NFAT transcriptional activity, EC50/IC50 evaluation of NFAT agonists/inducers/antagonists/inhibitors/inhibitory antibodies, and functional analysis of NFAT signaling pathways. Assay results will contain a written report and downloadable Excel- or Prism-based data.