Mouse Vascular Endothelial Growth Factor-120
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| Amount : | 100 µg |
| Purification : | Reducing and Non-Reducing SDS PAGE at >= 95% |
| Content : | Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA) Sterile water at 0.1 mg/mL |
| Storage condition : | Store at -20°C |
| AA sequence : | MAPTTEGEQK SHEVIKFMDV YQRSYCRPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCAGC CNDEALECVP TSESNITMQI MRIKPHQSQH IGEMSFLQHS RCECRPKKDR TKPEKCDKPR R |
Source: Genetically modified E.coli.
Predicted MW:Â Dimer, 14.2/28.4 kDa (121/242 aa)
Vascular endothelial growth factor A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. Â VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. Â Mouse VEGF-A has several alternatively spliced isoforms, with one being VEGF-120. Â VEGF-120 is an angiogenic factor that is expressed throughout endochondral bone development and is important during skeletogenesis.
Predicted MW:Â Dimer, 14.2/28.4 kDa (121/242 aa)
Vascular endothelial growth factor A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. Â VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. Â Mouse VEGF-A has several alternatively spliced isoforms, with one being VEGF-120. Â VEGF-120 is an angiogenic factor that is expressed throughout endochondral bone development and is important during skeletogenesis.
Endotoxin: Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
Centrifuge vial before opening, Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws. Upon reconstitution, a small amount of visible precipitate can be expected. A 10% overfill has been added to the total material vialed to compensate for this loss.  Â
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cell membrane |
| Tissue Specificity: | In developing embryos, expressed mainly in the choroid plexus, paraventricular neuroepithelium, placenta and kidney glomeruli. Also found in bronchial epithelium, adrenal gland and in seminiferous tubules of testis. High expression of VEGF continues in kidney glomeruli and choroid plexus in adults. |
| BioGrid: | 204512. 3 interactions. |
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