Mouse Monoclonal Antibody to UBC9 (Clone: 67AT1273.95.90)(Discontinued)

Product code: 10-6522

Clone name : 67AT1273.95.90
Clonality : Monoclonal
Application : WB
Reactivity : Human, Mouse, Rat

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Format : Purified
Amount : 400 µl
Isotype : Mouse IgG1
Purification : Protein G Chromatography
Content : Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Storage condition : Maintain refrigerated at 2-8°C for up to 2 weeks. For long term store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene : UBE2I
Gene ID : 7329
Uniprot ID : P63279
Alternative Name : SUMO-conjugating enzyme UBC9, 632-, SUMO-protein ligase, Ubiquitin carrier protein 9, Ubiquitin carrier protein I, Ubiquitin-conjugating enzyme E2 I, Ubiquitin-protein ligase I, p18, UBE2I, UBC9, UBCE9
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene.

WB~1:100~2000

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Nucleus, Cytoplasm
Post transnational modification: Phosphorylation at Ser-71 significantly enhances SUMOylation activity.
Tissue Specificity: Expressed in heart, skeletal muscle, pancreas, kidney, liver, lung, placenta and brain. Also expressed in testis and thymus.
BioGrid: 113177. 460 interactions.
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