Mouse Monoclonal Antibody to Thyroid Peroxidase(Clone: MoAb47)(Discontinued)

Product code: 10-11557

Clone name : MoAb47
Clonality : Monoclonal
Application : IHC
Reactivity : Human

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For estimated delivery dates, please contact us at [email protected]


Format : T.C. Sup.
Amount : 0.5 ml
Isotype : Mouse IgG1
Content : This antibody is supplied as tissue culture supernatant containing sodium azide as preservative.
Storage condition : Store at 2-8°C.
Gene : TPO
Gene ID : 7173
Uniprot ID : P07202
Alternative Name : TPO
Immunogen Information : Human thyroid peroxidase (hTPO) purified from thyroid microsomes by immunoaffinity chromatography.

Thyroid peroxidase (TPO) is a transmembrane protein of 107kDa containing a heme prosthetic group. It is present as a dimer on the apical surface of thyroid follicular cells. TPO is the primary enzyme involved in thyroid hormone synthesis. Malignant thyroid tumors exhibit an anomaly in TPO resulting in lower affinity for anti-TPO. This antibody may aid in the differentiation between benign and malignant thyroid tumors.

IHC : 1:10-1:25

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cell surface
Post transnational modification: Cleaved in its N-terminal part.
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