Mouse Monoclonal Antibody to Phospho-Histone H3(S10) (Clone: 44AT1232)(Discontinued)(Discontinued)

Product code: 10-6517

Clone name : 44AT1232
Clonality : Monoclonal
Application : WB
Reactivity : Mouse, Human

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Format : Purified
Amount : 400 µl
Isotype : Mouse IgG1
Purification : Protein G Chromatography
Content : Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Storage condition : Maintain refrigerated at 2-8°C for up to 2 weeks. For long term store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene : H3F3A
Gene ID : 3020;3021
Uniprot ID : P84243
Alternative Name : Histone H33, H3F3A, H33A, H3F3
Immunogen Information : Synthetic Peptide

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene contains introns and its mRNA is polyadenylated, unlike most histone genes. The protein encoded is a replication-independent member of the histone H3 family.

WB~1:100~500

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Nucleus, Chromosome
Post transnational modification: Butyrylation of histones marks active promoters and competes with histone acetylation. It is present during late spermatogenesis.
BioGrid: 109273. 18 interactions.
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