Mouse Monoclonal Antibody to Phospho-Histone H3(S10) (Clone: 44AT1232)(Discontinued)(Discontinued)
Figure 1: Western blot analysis of extracts from HL60 cells treated with 100nM of calyculin using Histone H3-pS10 Antibody (10-6517).
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| Format : | Purified |
| Amount : | 400 µl |
| Isotype : | Mouse IgG1 |
| Purification : | Protein G Chromatography |
| Content : | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| Storage condition : | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene contains introns and its mRNA is polyadenylated, unlike most histone genes. The protein encoded is a replication-independent member of the histone H3 family.
WB~1:100~500
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Nucleus, Chromosome |
| Post transnational modification: | Butyrylation of histones marks active promoters and competes with histone acetylation. It is present during late spermatogenesis. |
| BioGrid: | 109273. 18 interactions. |
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