Mouse Monoclonal Antibody to p27kip1(Clone: DCS-72.F6)(Discontinued)

Product code: 10-11552

Clone name : DCS-72.F6
Clonality : Monoclonal
Application : IHC
Reactivity : Human

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Format : Purified
Amount : 0.5 ml
Isotype : Mouse IgG1
Content : This antibody is supplied as purified immunoglobulin fraction containing sodium azide as preservative.
Storage condition : Store at 2-8°C.
Gene : CDKN1B
Gene ID : 1027
Uniprot ID : P46527
Alternative Name : Cyclin-dependent kinase inhibitor p27, p27Kip1, KIP1
Immunogen Information : BALB/C mice were injected with mouse recombinant p27 protein.

This antibody is specific to a protein of 27 kDa known as p27Kip1 a cell cycle regulatory mitotic inhibitor. This antibody recognizes an epitope between amino acids 83-204 of p27. This antibody does not show any cross-reactivity with other related mitotic inhibitors.

IHC : 1:25-1:50

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Nucleus, Cytoplasm, Endosome
Post transnational modification: Subject to degradation in the lysosome. Interaction with SNX6 promotes lysosomal degradation (By similarity).
Tissue Specificity: Expressed in all tissues tested. Highest levels in skeletal muscle, lowest in liver and kidney.
BioGrid: 107461. 94 interactions.
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