Mouse Monoclonal Antibody to p27kip1(Clone: DCS-72.F6)(Discontinued)
Figure 1 : Formalin fixed paraffin embedded human colon carcinoma stained with p27Kip1 antibody ( 10-11552).
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Format : | Purified |
Amount : | 0.5 ml |
Isotype : | Mouse IgG1 |
Content : | This antibody is supplied as purified immunoglobulin fraction containing sodium azide as preservative. |
Storage condition : | Store at 2-8°C. |
This antibody is specific to a protein of 27 kDa known as p27Kip1 a cell cycle regulatory mitotic inhibitor. This antibody recognizes an epitope between amino acids 83-204 of p27. This antibody does not show any cross-reactivity with other related mitotic inhibitors.
IHC : 1:25-1:50
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
Subcellular location: | Nucleus, Cytoplasm, Endosome |
Post transnational modification: | Subject to degradation in the lysosome. Interaction with SNX6 promotes lysosomal degradation (By similarity). |
Tissue Specificity: | Expressed in all tissues tested. Highest levels in skeletal muscle, lowest in liver and kidney. |
BioGrid: | 107461. 94 interactions. |
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