Mouse Monoclonal Antibody to NLRP12 (Clone: 228CT4.1.3)(Discontinued)
Figure 1: Western blot analysis of NLRP12/MB10187 antibody (10-6552) in mouse brain tissue lysates (35μg/lane). This demonstrates the NLRP12/MB10187 antibody detected the NLRP12/MB10187 protein.
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| Format : | Purified |
| Amount : | 400 µl |
| Isotype : | Mouse IgM,Kappa |
| Purification : | Protein G Chromatography |
| Content : | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| Storage condition : | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term store at -20°C in small aliquots to prevent freeze-thaw cycles. |
This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined.
WB~1:500~1500
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cytoplasm |
| Tissue Specificity: | Detected only in peripheral blood leukocytes, predominantly in eosinophils and granulocytes, and at lower levels in monocytes. |
| BioGrid: | 124861. 5 interactions. |
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