Mouse Monoclonal Antibody To N-Cadherin (Clone: 8C11)

Product code: 10-7653

Clone name : 8C11
Clonality : Monoclonal
Application : IHC, FACS, WB
Reactivity : Mouse, Human

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  •   25 µg

  •  100 µg

  • $110.00 

  • $200.00 

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Shipping Info:

Order now and get it on Tuesday November 26, 2024

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Format : Purified
Amount : 100 µg
Isotype : Mouse IgG1 kappa
Purification : Affinity Chromatography
Content : 0.5 mg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide.
Storage condition : Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : CDH2
Gene ID : 1000
Uniprot ID : P19022
Immunogen Information : Recombinant human N-cadherin extracellular domain (exact sequence is proprietary)

N-cadherin(CD325)  is a 140 kD protein belongs to a transmembrane molecules that mediate calcium dependent intracellular adhesion. Its extracellular region consists of five EC domains and has one cytoplasmic domain. N-cadherin is involved in organogenesis and maintenance of organ architecture by contributing to the sorting of heterogeneous cell types and in the cell adhesion needed to form tissues. N-cadherin is expressed by stem cells, myeloblasts, endothelial cells, and fibroblasts, and also is expressed in neural and muscle tissues and some types of carcinoma cells. CD325 associates with the cytoskeleton trough catenin proteins.

 

Flow Cytometry: 0.5-1 µg/10^6 cells, Immunofluorescence :1-2  µg/ml,  Western Blotting: 0.5-1.0 µg/ml, Immunohistology (Formalin-fixed) : 0.5-1.0 µg/ml; for 30 minutes at RT. (Optimal dilution for a specific application should be determined.)
 

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cell membrane, Cell membrane, Cell junction, Cell surface
Post transnational modification: May be phosphorylated by OBSCN.
BioGrid: 107435. 61 interactions.
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