Mouse Monoclonal Antibody to MMP9 (Clone: 331CT17.4.4)(Discontinued)
Figure 1: All lanes : Anti-MMP9 Antibody (10-6571) at 1:1000 dilution with Lane 1: HL-60 whole cell lysate and Lane 2: U937 whole cell lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 78 kDa.
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| Format : | Purified |
| Amount : | 400 µl |
| Isotype : | Mouse IgM |
| Content : | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS. |
| Storage condition : | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal
physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease
processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq].
WB~1:100~1000
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Secreted |
| Post transnational modification: | N- and O-glycosylated. |
| Tissue Specificity: | Detected in neutrophils (at protein level) (PubMed:7683678). Produced by normal alveolar macrophages and granulocytes. |
| BioGrid: | 110461. 18 interactions. |
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