Mouse Monoclonal Antibody to MGMT(Clone: MT3.1)(Discontinued)
Figure 1 : Formalin fixed paraffin embedded human tonsil stained with MGMT antibody ( 10-11541).
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| Format : | T.C. Sup. |
| Amount : | 0.5 ml |
| Isotype : | Mouse IgG1 |
| Content : | This antibody is supplied as tissue culture supernatant containing sodium azide as preservative. |
| Storage condition : | Store at 2-8°C. |
O(6)-methylguanine-DNA-methyltransferase (MGMT) is a 22 kDa human DNA repair protein that removes O(6)-alkylguanine DNA adducts. MGMT acts as a suicide acceptor protein repairing the DNA by accepting alkyl groups and consequently inactivating itself. This antibody stains all mantle zone lymphocytes and 50% of germinal center lymphocytes. Basaloid epithelial cells of tonsil squamous mucosa are also stained positive with this antibody.
IHC : 1:10-1:20
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Nucleus |
| BioGrid: | 110411. 74 interactions. |
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