Mouse Monoclonal Antibody to MAFK (Clone: 1328CT786.105.125)(Discontinued)
Figure 1: Flow cytometric analysis of Hela cells using MAFK Antibody (green) (10-6616) compared to an isotype control of mouse IgG1 (blue). MAFK Antibody was diluted at 1:25 dilution. An Alexa Fluor® 488 goat anti-mouse lgG at 1:400 dilution was used as the secondary antibody.
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| Format : | Purified |
| Amount : | 400 µl |
| Isotype : | Mouse IgG1,Kappa |
| Purification : | Protein G Chromatography |
| Content : | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| Storage condition : | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor.
FACS~1:25|| WB~1:1000
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Nucleus |
| BioGrid: | 113688. 18 interactions. |
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