Mouse Monoclonal Antibody to Hsp90 (Clone: 803CT9.1.2)(Discontinued)
Figure 1: Western blot analysis of Hsp90 Antibody (10-6621) with lysates Lane 1: Hela, Lane 2: K562, Lane 3: HepG2, Lane 4: mouse NIH/3T3, Lane 5: A2058, Lane 6: T47D cell line. Hsp90 Antibody was diluted at 1:1000 at each lane. A goat anti-mouse IgG H& L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20μg per lane.
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| Format : | Purified |
| Amount : | 400 µl |
| Isotype : | Mouse IgG1,Lambda |
| Purification : | Protein G Chromatography |
| Content : | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| Storage condition : | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
WB~1:1000
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Nucleus, Cytoplasm, Melanosome, Cell membrane |
| Post transnational modification: | S-nitrosylated; negatively regulates the ATPase activity and the activation of eNOS by HSP90AA1. |
| BioGrid: | 109552. 856 interactions. |
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