Mouse Monoclonal Antibody to Endoglin (CD105)(Clone :BS71)

Figure-1: CD105/endoglin stained tissue sections. Image (Figure-1) tonsil, (Figure-2) urinary bladder carcinoma and (Figure-3) ductal breast carcinoma sections have been stained using CD105/endoglin antibody (Clone: BS71) with 1:200 dilution. Excellent signal to noise ratio in vascular endothelia of tumor sections.

Mouse Monoclonal Antibody to Endoglin (CD105)(Clone :BS71)

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Figure-1: CD105/endoglin stained tissue sections. Image (Figure-1) tonsil, (Figure-2) urinary bladder carcinoma and (Figure-3) ductal breast carcinoma sections have been stained using CD105/endoglin antibody (Clone: BS71) with 1:200 dilution. Excellent signal to noise ratio in vascular endothelia of tumor sections.

Figure-2: CD105/endoglin stained tissue sections. Image (Figure-1) tonsil, (Figure-2) urinary bladder carcinoma and (Figure-3) ductal breast carcinoma sections have been stained using CD105/endoglin antibody (Clone: BS71) with 1:200 dilution. Excellent signal to noise ratio in vascular endothelia of tumor sections.

Figure-3: CD105/endoglin stained tissue sections. Image (Figure-1) tonsil, (Figure-2) urinary bladder carcinoma and (Figure-3) ductal breast carcinoma sections have been stained using CD105/endoglin antibody (Clone: BS71) with 1:200 dilution. Excellent signal to noise ratio in vascular endothelia of tumor sections.

Product code: 10-12544

Clone name :	BS71
Clonality :	Monoclonal
Application :	IHC
Reactivity :	Human

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Available Pack Size(s)

0.1 ml
0.5 ml

$689.00
~~$1,130.00~~ $960.50

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Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Amount :	0.5 ml
Isotype :	Mouse IgG1
Content :	TRIS with 0.03% sodium azide, pH7.2
Storage condition :	Store at 4°C


Gene :	Eng
Gene ID :	13805
Uniprot ID :	Q63961
Alternative Name :	ENG, END, ORW, HHT1, ORW1, CD105, FLJ41744

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia.

Immunohistochemical Analysis :-1:200

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location:

Cell membrane

Tissue Specificity:

Detected on blood vessels (at protein level) (PubMed:8194490). Detected on adult pulmonary artery, capillaries supporting the heart muscle and lung alveolar capillary endothelial cells (PubMed:10625534). Endoglin is restricted to endothelial cells in all tissues except bone marrow and is also found in stromal cells within the connective tissue of intestine, stomach, heart, skeletal muscle, uterus, ovary, oviduct, testis and thymus (PubMed:8194490).

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