Mouse Monoclonal Antibody to Desmin(Clone: D33)(Discontinued)
Figure 1 : Formalin fixed paraffin embedded human leiomyoma stained with Desmin antibody ( 10-11563).
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Shipping Info:
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| Format : | T.C. Sup. |
| Amount : | 0.5 ml |
| Isotype : | Mouse IgG1, Kappa |
| Content : | This antibody is supplied as tissue culture supernatant containing sodium azide as preservative. |
| Storage condition : | Store at 2-8°C. |
This antibody reacts with desmin protein of 53 kDa. Both striated as well as smooth muscle cells stain well with this antibody. The antibody shows a broad interspecific cross-reactivity, reacting with human.
IHC : 1:20-1:40
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cytoplasm, Cytoplasm, Cell membrane, Nucleus |
| Post transnational modification: | Phosphorylation at Ser-7, Ser-28 and Ser-32 by CDK1, phosphorylation at Ser-60 by AURKB and phosphorylation at Thr-76 by ROCK1 contribute to efficient separation of desmin intermediate filaments during mitosis. |
| BioGrid: | 108038. 47 interactions. |
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