Mouse Monoclonal Antibody to Cytokeratin 7(Clone: OV-TL 12/3)(Discontinued)
Figure 1 : Formalin fixed paraffin embedded human lung stained with Cytokeratin 7 antibody ( 10-11562).
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| Format : | Purified |
| Amount : | 0.5 ml |
| Isotype : | Mouse IgG1, Kappa |
| Content : | This antibody is supplied as purified immunoglobulin containing sodium azide as preservative. |
| Storage condition : | Store at 2-8°C. |
This antibody recognizes keratin polypeptide of 54 kDa. It stains a number of epithelial cells including ductal and glandular epithelia. Stratified squamous epithelia are positive but transitional epithelium of the urinary tract does not show any staining. This antibody labels adenocarcinomas and transitional carcinomas but does not react with squamous cell carcinomas.
IHC : 1:25-1:100
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cytoplasm |
| Post transnational modification: | Arg-20 is dimethylated, probably to asymmetric dimethylarginine. |
| Tissue Specificity: | Expressed in cultured epidermal, bronchial and mesothelial cells but absent in colon, ectocervix and liver. Observed throughout the glandular cells in the junction between stomach and esophagus but is absent in the esophagus. |
| BioGrid: | 110053. 16 interactions. |
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