Mouse Monoclonal Antibody to CD79a(Clone: HM47/A9)(Discontinued)
Figure 1 : Formalin fixed paraffin embedded human tonsil stained with CD79a Antigen ( 10-11533).
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Format : | Purified |
Amount : | 0.5 ml |
Isotype : | Mouse IgG1, Kappa |
Content : | This antibody is supplied as purified immunoglobulin fraction containing sodium azide as preservative. |
Storage condition : | Store at 2-8°C. |
Gene : | CD79A |
Gene ID : | 973 |
Uniprot ID : | P11912 |
Alternative Name : | Ig-alpha, MB-1 membrane glycoprotein, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein, CD79a, IGA, MB1 |
Immunogen Information : | Synthetic polypeptide consisting of the amino acid sequence GTYQDVGSLNIADVQ. |
This antibody is specific to human CD79a antigen complex, consisting of two polypeptides non-covalently associated with membrane-bound immunoglobulins on B cells. This complex of polypeptide and immunoglobulins constitute the B cell antigen receptor. The two components of this complex are designated CD79a and CD79b. The CD79a antigen appears at the pre-B cell stage, early in maturation and persists until the plasma cell stage. The CD79a antigen is found in majority of acute leukemias of precursor B cell type, in B cell lines and B cell lymphomas.
IHC : 1:50-1:100
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
Subcellular location: | Cell membrane |
Post transnational modification: | Arginine methylation in the ITAM domain may interfere with the binding of SYK. It promotes signals leading to B-cell differentiation (By similarity). |
Tissue Specificity: | B-cells. |
BioGrid: | 107411. 53 interactions. |
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