Mouse Monoclonal Antibody to CD79a(Clone: HM47/A9)(Discontinued)

Product code: 10-11533

Clone name : HM47/A9
Clonality : Monoclonal
Application : IHC
Reactivity : Human

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Format : Purified
Amount : 0.5 ml
Isotype : Mouse IgG1, Kappa
Content : This antibody is supplied as purified immunoglobulin fraction containing sodium azide as preservative.
Storage condition : Store at 2-8°C.
Gene : CD79A
Gene ID : 973
Uniprot ID : P11912
Alternative Name : Ig-alpha, MB-1 membrane glycoprotein, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein, CD79a, IGA, MB1
Immunogen Information : Synthetic polypeptide consisting of the amino acid sequence GTYQDVGSLNIADVQ.

This antibody is specific to human CD79a antigen complex, consisting of two polypeptides non-covalently associated with membrane-bound immunoglobulins on B cells. This complex of polypeptide and immunoglobulins constitute the B cell antigen receptor. The two components of this complex are designated CD79a and CD79b. The CD79a antigen appears at the pre-B cell stage, early in maturation and persists until the plasma cell stage. The CD79a antigen is found in majority of acute leukemias of precursor B cell type, in B cell lines and B cell lymphomas.

IHC : 1:50-1:100

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cell membrane
Post transnational modification: Arginine methylation in the ITAM domain may interfere with the binding of SYK. It promotes signals leading to B-cell differentiation (By similarity).
Tissue Specificity: B-cells.
BioGrid: 107411. 53 interactions.
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