Mouse Monoclonal Antibody to CD10/Calla(Clone :BS1)
Figure-1: FFPE sections of tonsil, kidney and liver have been stained using CD10 antibody (Clone:BS1), 1:300 dilution. Hue of the DAB has been increased using CuSO4 post enhancement method.
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| Amount : | 0.5 ml |
| Isotype : | Mouse IgG2b |
| Content : | TRIS with 0.03% sodium azide, pH7.2 |
| Storage condition : | Store at 4°C |
CD10 is a 100kDa glycoprotein, also designated Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, BurkittÂ’s, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.
Immunohistochemical Analysis :-1:300
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cell membrane |
| Post transnational modification: | Glycosylation at Asn-628 is necessary both for surface expression and neutral endopeptidase activity. |
| BioGrid: | 110455. 102 interactions. |
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