Mouse Monoclonal Antibody to Androgen Receptor(Clone: AR 441)(Discontinued)
Figure 1 : Formalin fixed paraffin embedded human prostate stained with Androgen Receptor antibody ( 10-11521).
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Shipping Info:
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| Format : | Purified |
| Amount : | 0.5 ml |
| Isotype : | Mouse IgG1 |
| Content : | This antibody is supplied as purified immunoglobulin fraction containing sodium azide as preservative. |
| Storage condition : | Store at 2-8°C. |
This antibody is specific to a protein of 110 kDa, identified as androgen receptor. This antibody reacts with full length AR and also with the newly described A form of the receptor. This antibody does not cross-react with estrogen, progesterone or glucocorticoid receptors.
IHC : 1:25-1:50
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Nucleus, Cytoplasm |
| Post transnational modification: | Palmitoylated by ZDHHC7 and ZDHHC21. Palmitoylation is required for plasma membrane targeting and for rapid intracellular signaling via ERK and AKT kinases and cAMP generation. |
| Tissue Specificity: | Isoform 2 is mainly expressed in heart and skeletal muscle (PubMed:15634333). Isoform 3 is expressed by basal and stromal cells of prostate (at protein level) (PubMed:19244107). |
| BioGrid: | 106862. 284 interactions. |
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