Mouse Monoclonal Antibody to Androgen Receptor(Clone: AR 441)(Discontinued)

Figure 1 : Formalin fixed paraffin embedded human prostate stained with Androgen Receptor antibody ( 10-11521).

Mouse Monoclonal Antibody to Androgen Receptor(Clone: AR 441)(Discontinued)

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Product code: 10-11521

Clone name :	AR 441
Clonality :	Monoclonal
Application :	IHC
Reactivity :	Human

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Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Format :	Purified
Amount :	0.5 ml
Isotype :	Mouse IgG1
Content :	This antibody is supplied as purified immunoglobulin fraction containing sodium azide as preservative.
Storage condition :	Store at 2-8°C.


Gene :	AR
Gene ID :	367
Uniprot ID :	P10275
Alternative Name :	Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4, DHTR, NR3C4
Immunogen Information :	BALB/C mice were injected with a synthetic peptide corresponding to the human androgen receptor.

This antibody is specific to a protein of 110 kDa, identified as androgen receptor. This antibody reacts with full length AR and also with the newly described A form of the receptor. This antibody does not cross-react with estrogen, progesterone or glucocorticoid receptors.

IHC : 1:25-1:50

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location:	Nucleus, Cytoplasm
Post transnational modification:	Palmitoylated by ZDHHC7 and ZDHHC21. Palmitoylation is required for plasma membrane targeting and for rapid intracellular signaling via ERK and AKT kinases and cAMP generation.
Tissue Specificity:	Isoform 2 is mainly expressed in heart and skeletal muscle (PubMed:15634333). Isoform 3 is expressed by basal and stromal cells of prostate (at protein level) (PubMed:19244107).
BioGrid:	106862. 284 interactions.