Mouse Monoclonal Antibody to AFP (N-term)(Clone: 143CT50.11.8)(Discontinued)

Product code: 10-6532

Clone name : 143CT50.11.8
Clonality : Monoclonal
Application : WB
Reactivity : Human

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Format : Purified
Amount : 400 µl
Isotype : Mouse IgM
Purification : Protein G Chromatography
Content : Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Storage condition : Maintain refrigerated at 2-8°C for up to 2 weeks. For long term store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene : AFP
Gene ID : 174
Uniprot ID : P02771
Alternative Name : Alpha-fetoprotein, Alpha-1-fetoprotein, Alpha-fetoglobulin, AFP, HPAFP
Immunogen Information : Synthetic Peptide
alpha 1 Fetoprotein encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

WB~1:100~1000

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Secreted
Post transnational modification: Sulfated.
Tissue Specificity: Plasma. Synthesized by the fetal liver and yolk sac.
BioGrid: 106682. 11 interactions.
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