Mouse Monoclonal Antibody to AFP (N-term)(Clone: 143CT50.11.8)(Discontinued)
Figure 1: Anti- AFP antibody (10-6532) at 1:1000 dilution + HepG2 whole cell lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 69 kDa.
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Format : | Purified |
Amount : | 400 µl |
Isotype : | Mouse IgM |
Purification : | Protein G Chromatography |
Content : | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
Storage condition : | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term store at -20°C in small aliquots to prevent freeze-thaw cycles. |
alpha 1 Fetoprotein encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
WB~1:100~1000
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
Subcellular location: | Secreted |
Post transnational modification: | Sulfated. |
Tissue Specificity: | Plasma. Synthesized by the fetal liver and yolk sac. |
BioGrid: | 106682. 11 interactions. |
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