Mouse Monoclonal Antibody to ACOX1 (Clone: 153CT43.1.1)(Discontinued)

Product code: 10-6537

Clone name : 153CT43.1.1
Clonality : Monoclonal
Application : WB, IHC-P, IF
Reactivity : Human

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Format : Purified
Amount : 400 µl
Isotype : Mouse IgG1
Purification : Protein G Chromatography
Content : Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Storage condition : Maintain refrigerated at 2-8°C for up to 2 weeks. For long term store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene : ACOX1
Gene ID : 51
Uniprot ID : Q15067
Alternative Name : Peroxisomal acyl-coenzyme A oxidase 1, AOX, Palmitoyl-CoA oxidase, Straight-chain acyl-CoA oxidase, SCOX, ACOX1, ACOX
Immunogen Information : Recombinant Protein
ACOX1 is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids.

WB~1:1000|| IHC-P~1:10~50|| IF~1:10~50

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Peroxisome
Tissue Specificity: Widely expressed with highest levels of isoform 1 and isoform 2 detected in testis. Isoform 1 is expressed at higher levels than isoform 2 in liver and kidney while isoform 2 levels are higher in brain, lung, muscle, white adipose tissue and testis. Levels are almost equal in heart.
BioGrid: 106567. 44 interactions.
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