Mouse CD45 Protein, His Tag

Product code: 32-18525

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  •   50 µg

  •  100 µg

  • $503.00 

  • $618.00 

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Amount : 100 µg
Purification : The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Content : Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.
Storage condition : Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Uniprot ID : P06800
Alternative Name : Ptprc;B220;L-CA;Ly-5;T200;CD45R;Lyt-4
Description :Recombinant mouse CD45 protein with C-terminal 6×His tag
Background : Enables several functions, including heparan sulfate proteoglycan binding activity; heparin binding activity; and protein tyrosine phosphatase activity. Involved in several processes, including lymphocyte differentiation; positive regulation of macromolecule metabolic process; and regulation of signal transduction. Acts upstream of or within several processes, including lymphocyte differentiation; positive regulation of lymphocyte activation; and regulation of protein phosphorylation. Located in external side of plasma membrane; focal adhesion; and membrane raft. Is expressed in several structures, including 3rd branchial arch; alimentary system; cardiovascular system; hemolymphoid system; and placenta. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in hepatitis C; multiple sclerosis; severe combined immunodeficiency; and severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive. Orthologous to human PTPRC (protein tyrosine phosphatase receptor type C).
Molecular Characterization: mass of 59.5 kDa after removal of the signal peptide. The apparent molecular mass of mCD45-His is approximately 130-250 kDa due to glycosylation.
Tag :C-6×His Tag
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