Monoclonal Antibody to SOX11 (Clone: ABM45D9)
Figure-1: Western blot analysis of Sox11. Anti-Sox11 antibody (Clone: ABM45D9) was tested at 0.5 µg/ml on A431, human Kidney and Y79 lysates.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Mouse IgG2b Kappa |
| Purification : | Protein G Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles. |
SOX11 (Sex determining region Y-box 11), located on chromosome 2p25, belong to the family of genes SOXC. It is a transcript factor involved in the embryonic neurogenesis and tissue remodeling, also participating in the control of cell proliferation. It is involved in gastrulation and in malignant diseases. It is expressed in foetal and neoplastic brain tissue, including gliomas (23619925). SOX11 is overexpressed in several solid tumors and in the vast majority of aggressive mantle cell lymphomas (MCLs). Diseases associated with SOX11 include mental retardation, autosomal dominant, 27 and coffin-siris syndrome.
Western blot analysis: 0.5-1 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Nucleus |
| Tissue Specificity: | Expressed mainly in the nervous system, brain (fetus and adult) and hear (adult). |
| BioGrid: | 112547. 1 interactions. |
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