Monoclonal Antibody to Sex Hormone Binding Globulin (SHBG)(Clone : SHBG/245)

Product code: 36-1675

Clone name : SHBG/245
Clonality : Monoclonal
Application : ELISA, IHC
Reactivity : Human

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100 µg
$520.00 

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Format : Purified
Amount : 100 µg
Isotype : Mouse IgG1, kappa
Purification : Affinity Chromatography
Content : 100 µg in 500 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : SHBG
Gene ID : 6462
Uniprot ID : P04278
Alternative Name : SHBG
Immunogen Information : Recombinant full-length human SHBG protein
Recognizes a protein of 45kDa, identified as SHBG. It functions as an androgen transport protein, but may also be involved in receptor-mediated processes. Each dimer binds one molecule of steroid. It is specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. SHBG regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.

ELISA (For coating, order Ab without BSA); ,Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes),

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Secreted
Post transnational modification: Variant Asn-356 contains one N-linked (GlcNAc...) at position 356.
Tissue Specificity: Isoform 1 and isoform 2 are present in liver and testis.
BioGrid: 112359. 58 interactions.
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