Monoclonal Antibody to RunX3 (Clone: ABM28D1)
Figure-1: Western blot analysis of RunX3. Anti- RunX3 antibody (Clone: ABM28D1) was used at 2 µg/ml on (1) HL-60 and (2) Jurkat lysates.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Mouse IgG2b Kappa |
| Purification : | Protein G Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
Runt-related transcription factor 3 (Runx3) forms a heterodimer of alpha and beta subunit and binds to the core of the promoter to regulate the transcription. It plays an important role in tumor suppressor and the gene is frequently deleted or transcriptionally silenced during tumor development. It has multiple isoforms coded by multiple transcript variances.
Western blot analysis: 2-4 µg/ml, Flowcytometry analysis: 0.5-1 µg/10^6 Cells
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Nucleus, Cytoplasm |
| Post transnational modification: | Phosphorylated on tyrosine residues by SRC. Phosphorylated by LCK and FYN. |
| Tissue Specificity: | Expressed in gastric cancer tissues (at protein level). |
| BioGrid: | 107312. 30 interactions. |
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