Monoclonal Antibody to Rat CD8b NALE™ Purified (Clone: 341)

Product code: 43-1046

Clone name : 341
Clonality : Monoclonal
Application : FACS
Reactivity : Rat

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500 µg
$850.00 

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For estimated delivery dates, please contact us at [email protected]


Amount : 500 µg
Isotype : Mouse IgG1, kappa
Content : 1 mg/ml in Phosphate-buffered aqueous solution, ph7.2.
Storage condition : The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Gene : Cd8b
Gene ID : 24931
Uniprot ID : P05541
Alternative Name : Cd8b1, CD8 antigen 37 kDa chain, OX-8 membrane antigen

The 341 monoclonal antibody specifically reacts with the beta chain of the Rat CD8 molecule. The alpha and beta chains of the CD8 molecule form a heterodimer common on most thymocytes. The CD8 positive T cells of athymic rats and most NK cells express a homodimer composed solely of CD8a. It is reported that macrophages express CD8 alpha and beta chains for signal transduction. CD8 is an antigen co-receptor that interacts with MHC class I molecules on antigen-presenting cells.

The antibody has been analyzed for quality through the flow cytometric analysis of the relevant cell type. It is recommended that the reagent be titrated for optimal performance for each application.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cell membrane
Post transnational modification: Palmitoylated at the cytoplasmic tail and thereby targets the heterodimer CD8A/CD8B to lipid rafts unlike CD8A homodimers.
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