Monoclonal Antibody to Mouse TIM-3 (Clone: ABM3F21)
Figure-1:Intra cellular Flow analysis of mTIM-3 in Raw cells using 1 µg/10^6 cells of mTIM-3 antibody (Clone: ABM3F21). Green represents isotype control; red represents anti-mTIM-3 antibody. Goat anti-Rat FITC conjugate was used as secondary antibody.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Rat IgG1, Kappa |
| Purification : | Protein G Chromatography |
| Content : | 100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles |
| Gene : | Havcr2 |
| Gene ID : | 171285 |
| Uniprot ID : | Q8VIM0 |
| Alternative Name : | Hepatitis A virus cellular receptor 2, HAVcr-2, T-cell immunoglobulin and mucin domain-containing protein 3, T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3 |
| Immunogen Information : | Partial length recombinant TIM-3 protein was used as the immunogen for this antibody. |
Facs: 2-4 µg/10^6 cells
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Secreted |
| Post transnational modification: | N-glycosylated. |
| Tissue Specificity: | Expressed in T-helper type 1 lymphocytes. Not expressed by naive T-cells but up-regulated as they differentiate into T-helper-1 cells. Also expressed by differentiated type 1 CD8+ cytotoxic T-cells. Expressed on peritoneal exudate macrophages, monocytes, and splenic dendritic cells (DCs). Expression on natural killer (NK) cells is inversely associated with IFN-gamma production during the initial 24 h of LPS-induced endotoxic shock. Expressed on mast cells. |
| BioGrid: | 228588. 1 interactions. |
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