Monoclonal Antibody to Mouse IL-1 alpha NALE™ Purified (Clone: ALF-161)
Roll over image to zoom in
Shipping Info:
For estimated delivery dates, please contact us at [email protected]
| Amount : | 500 µg |
| Isotype : | Armenian Hamster IgG |
| Content : | 1 mg/ml in Phosphate-buffered aqueous solution, ph7.2. |
| Storage condition : | The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. |
IL-1 Alpha is a non-secreted, proinflammatory cytokine produced in a variety of cells, including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1 Alpha and IL-1 Beta bind to the same receptor and have similar, if not identical, biological properties. These cytokines have a broad range of activities including the stimulation of thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity, and the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1 Beta is a secreted cytokine, IL-1 Alpha is predominantly a cell-associated cytokine. The ALF-161 monoclonal antibody reacts with the precursor, secreted and membrane-associated forms of mouse IL-1 Alpha. The antibody is reported to be usable as the capture antibody in an ELISA assay and exhibits neutralization properties.
The antibody has been analyzed for quality through the flow cytometric analysis of the relevant cell type. It is recommended that the reagent be titrated for optimal performance for each application.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Secreted |
| BioGrid: | 200623. 1 interactions. |
|
There are currently no product reviews
|
.png "ACE2/HEK293 Stable Cell Line")
