Monoclonal antibody to Mouse ICOS (Clone: 7E.17G9)
Figure 1: Cell surface staying of splenocytes stimulated with ConA + mIL2 for 3 days. Green represents Rat isotope control, red represents Anti-mouse Icos (10-7642). 0.2 µgantibodies were used. Goat anti-rat PE was used as secondary antibody.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Rat IgG2b, Kappa |
| Purification : | Protein G Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles. |
| Gene : | Icos |
| Gene ID : | 54167 |
| Uniprot ID : | Q9WVS0 |
| Alternative Name : | Inducible T-cell costimulator, Activation-inducible lymphocyte immunomediatory molecule, CD28 and CTLA-4-like protein, CCLP, CRP-1 |
| Immunogen Information : | Mouse ICOS cDNA and ICOS hexahistidine fusion protein wasused the immunogen for this antibody. |
Flowcytometric Analysis: 0.2-0.4 µg/10^6 Cells
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Membrane |
| Post transnational modification: | N-glycosylated. |
| Tissue Specificity: | Expressed on activated T-cells and resting memory T-cells. High expression seen in the thymic medulla and in the germinal centers and T-cell zones of lymph nodes and Peyer patches. Expressed at low levels in the spleen. |
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