Monoclonal Antibody to Mouse CTLA-4 (Clone: 9H10)
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Amount : | 100 µg |
Isotype : | Syrian Hamster IgG |
Purification : | Protein G Chromatography |
Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
Storage condition : | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles. |
Subcellular location: | Cell membrane |
Post transnational modification: | Phosphorylation at Tyr-201 prevents binding to the AP-2 adapter complex, blocks endocytosis, and leads to retention of CTLA4 on the cell surface. |
Tissue Specificity: | Widely expressed with highest levels in lymphoid tissues. |
BioGrid: | 198575. 1 interactions. |
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