Monoclonal Antibody to Insulin (Clone: 2D11-H5)
Fig: 1 Immunohistochemical analysis of Insulin in human pancreas using Insulin antibody (Clone: 2D11-H5) at 1:500 dilution.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Mouse IgG1, kappa |
| Purification : | Protein G Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles. |
Insulin is a secreted peptide hormone produced by the pancreas that regulates carbohydrate and lipid metabolism. Insulin is released from the pancreatic beta cells of the islets of Langerhans in response to secretagogues. Following its release, insulin quickly acts to both inhibit hepatic glucose production and stimulate peripheral blood glucose utilization. During this process cells in the liver, muscle, and fat are triggered to take up glucose and store it as glycogen, resulting in a decrease of blood glucose levels.
Flow Cytometry (1-2ug/million cells); Immunofluorescence (1-2ug/ml); Immunohistochemistry (Formalin-fixed) (0.1-0.2ug/ml for 30 minutes at RT)(No special pretreatment is required for staining of formalin/paraffin tissues.)
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Secreted |
| BioGrid: | 109842. 13 interactions. |
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