Monoclonal Antibody to IKK alpha (Clone: ABM10G9)
Figure-1: Western blot analysis of IKK alpha. Anti-IKK alpha antibody (Clone: ABM10G9) was used at 2 µg/ml on Hela, MCF7, U87, mSmall Intestine, PC3 and 293 lysates.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Mouse IgG1, Kappa |
| Purification : | Protein G Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
| Gene : | CHUK |
| Gene ID : | 1147 |
| Uniprot ID : | O15111 |
| Alternative Name : | Inhibitor of nuclear factor kappa-B kinase subunit alpha, I-kappa-B kinase alpha, Conserved helix-loop-helix ubiquitous kinase, Nuclear factor NF-kappa-B inhibitor kinase alpha, NFKBIKA, Transcription factor 16 |
| Immunogen Information : | Full length recombinant protein of IKK alpha was used as the immunogen for this antibody. |
WB: 2-4 µg/ml, FACS: 0.5-1 µg/10^6
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cytoplasm, Nucleus |
| Post transnational modification: | (Microbial infection) Acetylation of Thr-179 by Yersinia yopJ prevents phosphorylation and activation, thus blocking the I-kappa-B signaling pathway. |
| Tissue Specificity: | Widely expressed. |
| BioGrid: | 107569. 143 interactions. |
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