Monoclonal Antibody to IkB alpha (Clone: ABM11B7)
Figure-1: Intra cellular flow analysis of IkB alpha in Jurkat cell treated with PMA, using 0.5 µg/10^6 cells of antibody (Clone: ABM11B7). Green represents isotype control; red represents anti-IkB alpha antibody. Goat anti-mouse PE conjugate was used as secondary antibody.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Mouse IgG1, Kappa |
| Purification : | Protein G Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
| Gene : | NFKBIA |
| Gene ID : | 4792 |
| Uniprot ID : | P25963 |
| Alternative Name : | NF-kappa-B inhibitor alpha, I-kappa-B-alpha, Major histocompatibility complex enhancer-binding protein MAD3, IkappaBalpha |
| Immunogen Information : | A partial length recombinant IkB alpha protein (amino acids 28-309) was used as immunogen for this antibody. |
FACS: 0.5-1 µg/10^6
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cytoplasm, Nucleus |
| Post transnational modification: | Deubiquitinated by porcine reproductive and respiratory syndrome virus Nsp2 protein, which thereby interferes with NFKBIA degradation and impairs subsequent NF-kappa-B activation. |
| BioGrid: | 110859. 154 interactions. |
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