Monoclonal antibody to ICOS-ligand (Clone: ABM5E52 )
Figure1: Cell surface staining of CHO and CHO-IcosL cells (cat. 14-504ACL) using 0.5 µg of anti-ICOS ligand (cat. 10-7616) antibody. Green represents CHO cells, Red represents CHO-IcosL cells. Goat anti-mouse PE was used as secondary antibody.
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Format : | Purified |
Amount : | 100 µg |
Isotype : | Mouse IgG2b, Kappa |
Purification : | Protein G Chromatography |
Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
Storage condition : | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles |
Gene : | ICOSLG |
Gene ID : | 23308 |
Uniprot ID : | O75144 |
Alternative Name : | ICOS ligand, B7 homolog 2, B7-like protein Gl50, B7-related protein 1, B7H2, B7RP1, ICOSL, KIAA0653 |
Immunogen Information : | A partial length recombinant protein of ICOS-L (amino acid 02-272) was used as the immunogen for this antibody. |
Facs anaysis: 0.5-1 µg/10^6 Cells
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
Subcellular location: | Cell membrane |
Tissue Specificity: | Isoform 1 is widely expressed (brain, heart, kidney, liver, lung, pancreas, placenta, skeletal muscle, bone marrow, colon, ovary, prostate, testis, lymph nodes, leukocytes, spleen, thymus and tonsil), while isoform 2 is detected only in lymph nodes, leukocytes and spleen. Expressed on activated monocytes and dendritic cells. |
BioGrid: | 116900. 8 interactions. |
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