Monoclonal Antibody to Human CD85j (ILT2) NALE™ Purified (Clone: HP-F1)
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| Amount : | 100 µg |
| Isotype : | Mouse IgG1, kappa |
| Content : | 1 mg/ml in Phosphate-buffered aqueous solution, ph7.2. |
| Storage condition : | The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. |
The HP-F1 monoclonal antibody reacts with human CD85j, a 110 kDa single transmembrane glycoprotein. The CD85 molecules encompass a large immunoregulatory family called Leuokocyte Immunoglobulin-like Receptors (LIRs) and Ig-Like Transcripts (ILTs). CD85j is also knows as Ig-like transcpript (ILT2) and leukocyte Ig-like receptor (LIR-1). It is expressed on subsets of NK, B and T cells and on myeloid cells such as monocytes and dendritic cells. CD85j is involved in viral infections.
The antibody has been analyzed for quality through the flow cytometric analysis of the relevant cell type. It is recommended that the reagent be titrated for optimal performance for each application.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Secreted |
| Post transnational modification: | Phosphorylated on tyrosine residues. Dephosphorylated by PTPN6. |
| Tissue Specificity: | Expressed predominantly on B-cells and monocytes, and at lower levels on dendritic cells. Detected on a low percentage of T-cells and natural killer (NK) cells. |
| BioGrid: | 116070. 7 interactions. |
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